Table 1

Characteristics of stroke patients by leukoaraiosis.


Leukoaraiosis
Characteristics
Present (n = 307)
Absent (n = 287)
P value


Age (yr)
72.1 ± 9.8
61.1 ± 11.9
< 0.001

Gender


0.001

     Male (n = 342)
157 (45.9)
185 (54.1)


     Female (n = 252)
150 (59.5)
102 (40.5)


Hypertension (n = 383)
229 (59.8)
154 (40.2)
< 0.001

Diabetes mellitus (n = 236)
133 (56.4)
103 (43.6)
0.390

Hyperlipidemia (n = 193)
95 (49.2)
98 (50.8)
0.228

Heart disease (n = 105)
44 (41.9)
61 (58.1)
0.018

          Atrial fibrillation (n = 78)
34 (43.6)
44(56.4)
0.125

Regular cigarette smoking (n = 153)
57 (37.3)
96 (62.7)
< 0.001

Previous ischemic stroke (n = 87)
58 (66.7)
29 (33.3)
0.002

Stroke subtype


0.016

     Large artery disease(n = 297)
170 (57.2)
127 (42.8)
0.031a
0.006b
     Lacunar(n = 193)
93 (48.2)
100 (51.8)
0.198b

     Cardioembolic (n = 104)
44 (42.3)
60 (57.7)



Values represent mean ± SD and number of patients with percentages in parenthesis

The two groups were compared by two-sample t-test for continuous variables and chi-square test for nominal variables.

a Comparison is with lacunar group, based on the Chi-square test.

b Comparison is with cardioembolic group

Lee et al. BMC Neurology 2008 8:31   doi:10.1186/1471-2377-8-31