Table 3

Mean carnosinase activity in the without dementia, AD and MD groups after removal of medical conditions (Table 1)

Medical condition removed
Carnosinase (μmol/ml/h)


Without dementia
AD
MD

None
40.3
44.4
26.6**
Arthritis
35.8
47.0
22.0*
Cardiovascular disease
41.2
41.6
21.4*
Depression
41.5
44.5
26.2*
Diabetes
36.6
44.5
28.7*
Hypothyroidism, treated
40.3
42.6
26.6*
Parkinson's Disease
38.9
44.4
26.6**
Renal insufficiency
39.0
44.4
27.6*
Stroke, history
40.3
44.4
26.6**
TIA, history
39.0
43.2
19.4‡***

AD, Alzheimer's disease; MD, mixed dementia.

* p-value < 0.05, ** p-value = 0.01, *** p-value = 0.001 between AD and MD

‡ p-value = 0.01 between MD and without dementia

Balion et al. BMC Neurology 2007 7:38   doi:10.1186/1471-2377-7-38