Additional file 1.

Isoelectric focusing of serum transferrin and Apo C-III. A. Normal sialylation of transferrin (N-linked glycoprotein) in all four patients before IVIG (Pre), after IVIG loading (Mid), and after the treatment period (Post). Samples of patients 3 and 4 were electrophoresed on a gel different from the gel for samples 1 and 2. Transferrin sialo-isoforms are indicated by their charge (2–6). B. Normal sialylation of Apo C-III in all four patients before IVIG (Pre), after IVIG loading (Mid), and after the treatment period (Post). Normal control sera (NC₁ and NC₂) exhibit three bands; treatment with sialidase (S) reduces this to one main band and a minor band. Samples of patients 3 and 4 were electrophoresed on a gel different from the gel for samples 1 and 2. Apo C-III₀ = asialo-; Apo C-III₁ = monosialo-; Apo C-III₂ = disialo-Apo C-III isoforms.

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Sparks et al. BMC Neurology 2007 7:3   doi:10.1186/1471-2377-7-3