Table 1 |
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|
Patient baseline characteristics by group |
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|
Pre-Intervention |
Post-Intervention |
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|
Active (n = 33) |
Control (n = 36) |
Active (n = 23) |
Control (n = 29) |
|
|
|
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|
Males (%) |
62% |
51% |
||
|
Age (years) |
61 (10) |
66 (13) |
||
|
Prescribed levodopa (%) |
21 (62%) |
25 (71%) |
18 (78%) |
22 (76%) |
|
Levodopa dose (mg) |
485 (252) |
538 (389) |
511 (306) |
670 (380) |
|
Prescribed dopamine agonist (%) |
25 (74%) |
25 (71%) |
18 (78%) |
18 (62%) |
|
Change in levodopa equivalent units |
- |
- |
51 (148) |
70 (149) |
|
Number of PD drugs |
2.4 (1.1) |
2.4 (1.3) |
2.4 (1.2) |
2.2 (1.5) |
|
Number of PD daily doses |
4.0 (2.5) |
4.0 (1.3) |
4 (0.8) |
4 (1.2) |
|
Number of PD tablets per day |
9 (5) |
9.1 (5) |
9.5 (5) |
9 (5) |
|
Number of non-PD drugs per day |
2.6 (3) |
2.9 (1.8) |
2.5 (3) |
3.5 (4) |
|
Total number of tablets per day |
12 (5) |
12 (5) |
13 (7) |
12 (7) |
|
Number of patients with carer |
6 (18%) |
7 (19%) |
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|
Duration of PD (years) |
7.5 (6) |
6.3 (4.1) |
- |
- |
|
UPDRS 3 |
30 (12) |
24 (13) |
29 (14) |
28 (14) |
|
Hoehn & Yahr |
2.4 (0.7) |
2.4 (0.7) |
2.5 (0.7) |
2.5 (0.7) |
|
Schwab & England |
78 (10) |
76 (14) |
71 (18) |
73 (15) |
|
MMSE |
28 (2) |
28 (2) |
- |
- |
|
Geriatric depression score |
12 (6) |
10 (7) |
- |
- |
|
PDQ SI |
30 (15) |
26.5 (18) |
36 (15) |
28 (14) |
|
Timing adherence, median (IQ) |
17% (9–51) |
21% (10–59) |
39% (22–58) |
20% (10–47)* |
|
|
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|
Data are mean (standard deviation) unless otherwise stated. PD = Parkinson's disease, UPDRS = Unified Parkinson's disease rating scale, MMSE = mini mental state examination, PDQ 39 SI = Parkinson's disease quality of life single index, IQ = interquartile range. *p = 0.007. There were no other significant differences between groups. |
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|
Grosset and Grosset BMC Neurology 2007 7:20 doi:10.1186/1471-2377-7-20 |
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