Table 1

Key information from the community-based neuropathological studies of old age dementia

Study

Hisayama study

CC75C

Vantaa 85+

CFAS

HAAS

Cache County study


Nottingham

Gwynedd

Newcastle

Cambridgeshire

Oxford

Liverpool*


Start date

1985 (for dementia prevalence)

1985–1987

1991

1991–93

1989–91

1991–1993

1995–1997

Number of subjects eligible

1440 in 1992

2,835

601

16,261

6,028

4,678

5,677

Years for re-examination

yearly

1988–90

1991–92

1994–95

1998–99

2002–2003

1994

1996

1999

1992

1995

1998

2000

2002

1991–93

1997–98

1999

2002

1994–1996

1997–1999

2000–2001

2002–2003

2004- in progress

1998–2000

2004- in progress

Number of subjects followed initially (% of those eligible)

1436 (99.7%) in 1992

2609 (92%)

553 (92%)

13009 (80%)

5222 (87%)

3734 (79.8%)

5092 (89.7%)

Age at start of study, mean (range) in years

Men 73 (65–92)

Women 74 (65–98)

81 (75–106)

89 (85–90+)

75 (65–105)^

79 (65–108)

78 (71–93)

74 (65–90+)

% men at start of study

40

34

21

40

47

100

42

Number of brains collected

176 (1985–1992) + 105 (1998–2001)

225 (as of mid 2004)

305 (as of 2002)

370

103 (as of mid 2004)

559 (as of 2004)

65 (+5 whom have not completed clinical assessment) (as of 2002)


* different interviewing strategy than the other 5 centres

^ stratified to have equal numbers above and below 75

Zaccai et al. BMC Neurology 2006 6:2   doi:10.1186/1471-2377-6-2

Open Data