Table 3

Autozygosity mapping data generated by genotyping eight members of the two autosomal recessive spastic CP families. Subjects 4718, 4719, 4720 and 4722 represent family A; subjects 4578, 4579, 4581 and 4679 represent family B as demonstrated in Figure 2. This Table is organised according to the definitive marker order determined from current databases and the physical contig mapping undertaken. The minimum homozygous region is highlighted. *Denotes an unaffected family member.

Marker

Base position

4718

4719

4722*

4720*

4578

4579

4581

4679


D2S2157 AFMA119YH5

166029867

145

145

145/147

145

145/147

145/147

145/147

145/147

D2S124 AFM094ZC9

166347755

160

160

160

160

160/163

160/163

160/163

160/163

D2S2330 AFMC015YD9

166900134

156

156

156/158

156/158

160/168

160/168

160/168

160/168

CHLC.GATA71B02

167624503

240/256

240/256

240/256

240/256

240/256

240/256

240/256

240/256

D2S2345 AFM080XG9

168922932

156

156

150/156

150/156

152

152

152

152

CHLC.GATA71D01

169848018

193

193

193

193

193

193

193

193

D2S294 AFM205XF12

170579380

186

186

186

186

208

208

208

208

AFMA109YC1

171576976

256

256

254/256

256

254

254

254

254

D2S376 AFM319XG1

171576985

235

235

235

235

235

235

235

235

D2S2284 AFMB314YE1

171696071

166

166

166

166

166

166

166

166

D2S2177 AFMA155TF9

171790203

118

118

118

118

128

128

128

128

D2S2194 AFMA222XB9

171884139

141

141

141

141/143

145

145

145

145

D2S333 AFM2702E9

172592103

189

189

189/191

189/191

189

189

189

189

D2S2302 AFMB342ZD9

172758604

204

204

199/204

199/204

204

204

204

204

D2S2381 AFMA082TF5

172861090

222

222

226

222/226

224

224

224

224

D2S326 AFM266VE1

173299492

92

92

92

92

92

92

92

92

AFMA304WB1

176057526

130/132

122/132

130/132

122/132

124

124

124

124

D2S138 AFM176XD4

177947395

108

108

113

108/113

111/117

111

111

111

D2S148 AFM200WA11

178434054

184/188

184/188

184/194

184/194

188/190

186

186

186

D2S300 AFM214XC3

178826338

87/89

87/89

87/89

87/89

87/89

89

89

89


Lynex et al. BMC Neurology 2004 4:20   doi:10.1186/1471-2377-4-20

Open Data