|
Strength Outcomes. Studies Comparing Deflazacort and Prednisone. |
|||
| Study (Duration of Follow up) |
A. Bonifati, 2000 (12 months) |
F. Angelini, 1998 (12 months) |
N. Brooke, 1996 (3 months) |
|
|
|||
| Strength Measures |
|||
|
|
|||
| MRC score * (mean change in score from baseline) |
DFZ: + 1 Pred: + 0.5 No variance or P values reported. |
- |
- |
| Average Muscle score * (mean change in score from baseline) |
- |
- |
DFZ (low): +0.18 (+/- 0.4) DFZ (high): +0.26 (+/- 0.5) Pred: +0.27 (+/- 0.5) Standard errors imputed from p values. |
|
|
|||
| Functional Measures |
|||
|
|
|||
| Timed gait |
Measured but not reported. |
- |
- |
| Timed stairs |
- |
- |
- |
| Timed chair |
- |
- |
- |
| Timed Gower |
- |
- |
- |
| Graded gait ** |
DFZ: - 0.5 Pred: -0.5 Combined score from all four tests. No variance or p values reported. |
- |
- |
| Graded stairs ** |
- |
- |
- |
| Graded chair ** |
- |
- |
- |
| Graded Gower ** |
- |
- |
- |
|
|
|||
| Other Measures |
|||
|
|
|||
| Patient reported benefit |
- |
Patients reported benefit on both prednisone and DFZ. No numeric representation of reported benefit was reported. |
- |
|
A dash represents that this outcome measure was not used. MRC = Medical Research Council * For MRC score, MRC index and muscle score higher scores are more favorable. ** For Graded scores a lower score is more favorable. | |||
Campbell and Jacob BMC Neurology 2003 3:7 doi:10.1186/1471-2377-3-7 |
|||