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Open Access Research article

Association between osteoporosis and benign paroxysmal positional vertigo: a systematic review

Shudong Yu1, Fenye Liu2, Zhixin Cheng3 and Qirong Wang1*

Author Affiliations

1 Department of Otolaryngology, Shandong Qianfoshan Hospital, 16766 Jingshi Road, Jinan 250014, PR China

2 Department of Traditional Chinese Medicine, Shandong Provincial Hospital affiliated to Shandong University, Jinan, PR China

3 Department of Vascular Surgery, Shandong Traditional Chinese Medicine Hospital, Jinan, PR China

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BMC Neurology 2014, 14:110  doi:10.1186/1471-2377-14-110

Published: 20 May 2014



Increasing recent evidence has implicated osteoporosis as a risk factor for benign paroxysmal positional vertigo (BPPV). We conducted a systematic review to examine the association between osteoporosis and BPPV.


Four electronic databases (PubMed, EMBASE, Cochrane Library, and the China Network Knowledge Infrastructure) were searched to identify all papers, published in either English or Chinese, examining the association between osteoporosis (osteopenia) and BPPV.


Seven studies were eligible for analysis, though these studies included some weaknesses. Most of the studies demonstrated a correlation between osteoporosis (osteopenia) and the occurrence and recurrence of BPPV, especially in older women. Patients with osteoporosis may require more canalith-repositioning procedures.


This systematic review provides insight into currently available evidence and elucidates the possible existence of an association between BPPV and osteoporosis (osteopenia). However, the evidence supporting that conclusion is not strong, and further studies are needed to clarify the association between these conditions.

Osteoporosis; Osteopenia; Benign paroxysmal positional vertigo; Systematic review