25-OH- vitamin D serum levels. Serum 25-OH-D (25-hydroxy-vitamin D) was measured at baseline, 3, 6 and 12 month using a chemiluminescent immunoassay. The high dose supplementation resulted in significantly higher serum 25-OH-D levels compared to low dose throughout the follow up (P < 0.001). With high dose, 25-OH-D levels were significantly above baseline at all time points (P ≤ 0.01), while low dose resulted in significantly increased 25-OH-D levels compared to baseline only at 3 months (P = 0.006) and at 6 months (P = 0.04).
Golan et al. BMC Neurology 2013 13:60 doi:10.1186/1471-2377-13-60