Table 6

Frequency of tangle pathology scores for all ApoE genotypes
2/3 3/3 2/4 3/4 4/4
Frontal Tangle Density None 9 (4.1%) 57 (24.7%) 2 (15.4%) 35 (15%) 4 (6.7%)
Sparse 3 (13.6%) 62 (26.8%) 4 (26.7%) 39 (16.7%) 12 (20%)
Moderate 3 (13.6%) 22 (9.5%) 2 (15.4%) 31 (5.6%) 8 (13.3%)
Frequent 7 (31.8%) 90 (39%) 5 (38.5%) 129 (55.1%) 36 (60%)
Temporal Tangle Density None 4 (18.2%) 25 (10.9%) 2 (15.4%) 17 (7.2%) 0 (0%)
Sparse 6 (27.3%) 46 (20.1%) 2 (15.4%) 22 (9.4%) 7 (11.7%)
Moderate 2 (9%) 34 (14.8%) 1 (7.7%) 19 (8.1%) 7 (11.7%)
Frequent 10 (45.5%) 124 (54.1%) 8 (61.5%) 177 (75.3%) 46 (76.7%)
Parietal Tangle Density None 10 (45.5%) 64 (28.2%) 3 (23.1) 36 (15.4%) 5 (8.5%)
Sparse 2 (9%) 47 (20.7%) 3 (23.1) 36 (15.4%) 10 (5.9%)
Moderate 2 (9%) 25 (11%) 1 (7.7%) 31 (13.2%) 8 (13.6%)
Frequent 8 (36.4%) 91 (40.1%) 6 (46.1%) 131 (56%) 36 (61%)
Hippocampal Tangle Density None 3 (13.6%) 11 (4.8%) 1 (8.3%) 4 (1.7%) 0 (0%)
Sparse 1 (4%) 27 (11.8%) 0 (0%) 9 (3.8%) 4 (6.7%)
Moderate 3 (13.6%) 30 (13.2%) 1 (8.3%) 17 (7.2%) 2 (3%)
Frequent 15 (36.4%) 160 (70.2%) 10 (83.3%) 205 (87.2%) 54 (90%)
Entorhinal Tangle Density None 1 (13.6%) 11 (4.8%) 1 (7.7%) 0 (0%) 0 (0%)
Sparse 1 (4.5%) 27 (11.8%) 0 (0%) 3 (1.3%) 0 (0%)
Moderate 1 (13.6%) 30 (13.2%) 1 (7.7%) 7 (3.0%) 2 (3.3%)
Frequent 19 (0%) 160 (70.2%) 11 (84.6%) 223 (95.7%) 58 (96.7%)

n (% = percent).

Sabbagh et al.

Sabbagh et al. BMC Neurology 2013 13:44   doi:10.1186/1471-2377-13-44

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