Table 3

Baseline characteristics of study participants in the 183 included articles
All studies (n=183) Longitudinal studies (n=20) Cross-sectional studies (n=163) P value
Baseline demographics
  Median number of patients 32 (21 to 53) 31 (16 to 36) 34 (22 to 55) 0.058
  Mean age (years) 63.5 (5.6) 63.7 (6.7) 63.4 (5.5) 0.771
  Mean percentage male 58.7 (13.9) 67.3 (15.6) 57.7 (13.3) 0.002
  Median disease duration (years) 5.7 (3.6 to 7.4) 3.2 (1.7 to 5.9) 5.9 (4.1 to 7.6) 0.005
  Median percentage treated 76.8 (51.2 to 88.8) 40.6 (0.0 to 71.1) 78.5 (56.7 to 90.2) 0.005
Baseline disease severity
  Median total UPDRS 33.3 (29.4 to 40.6) 31.8 (30.1 to 38.7) 33.3 (29.4 to 40.6) 0.790
  Median UPDRS (II) 14.7 (11.6 to 16.3) 9.1 (Insufficient data for IQR) 14.8 (11.9 to 16.6) 0.023
  Median UPDRS (III) 21.0 (16.6 to 26.3) 22.4 (16.3 to 28.5) 20.9 (16.8 to 25.8) 0.864
  Median Hoehn & Yahr 2.5 (2.0 to 2.8) 1.8 (1.6 to 2.0) 2.5 (2.1 to 2.9) <0.001
  Median MMSE 25.8 (23.0 to 28.1) 25.5 (22.3 to 28.3) 25.8 (23.0 to 28.1) 1.000

Means are presented with standard deviations, and medians with interquartile ranges (IQR). The P value column relates to comparisons made between longitudinal and cross-sectional studies using the Mann–Whitney test.

McGhee et al.

McGhee et al. BMC Neurology 2013 13:35   doi:10.1186/1471-2377-13-35

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