ROC curve analysis of CSF CXCL13 levels to discriminate between Lyme neuroborreliosis patients and controls. Lyme neuroborreliosis patients from the cross-sectional study and the pre-treatment part of the longitudinal study. Controls include asymptomatic HIV patients and study subjects with no CNS infectious or inflammatory disease. Horizontal lines show different suggested cut-off levels for CSF CXCL13 (Tjernberg et al. 142 pg/mL, van Burgel et al. 250 pg/mL, and Schmidt et al. 1,229 pg/mL). 61 pg/mL was the chosen cut-off in this study.
Bremell et al. BMC Neurology 2013 13:2 doi:10.1186/1471-2377-13-2