Table 1

Baseline characteristic of trials participants
Source No. of patients Gender (male) Mean age, y Pre-existent diseases Diabetes Total cholesterol (mmol/L)
BIP study [8] (2000) 3090 2825 (91%) 60 MI more than 6 month, and less than 5 year and/or stable angina 10% 5.5
VA-HIT study [10] (1999) 2531 2531 (100%) 64 Histories of CHD 25% 4.5
Acheson J [17] (1972) 95 65 (68%) NR Cerebral vascular disease Excluded severe diabetics 7.5
Veterans Administration Cooperative Study Group [18] (1973) 532 532 (100%) NR cerebral I or TIA within 12 month 24% 6.2
Coronary Drug Project Research Group [19] (1975) 3892 3892 (100%) NR MI more than 3 month NR 6.5
WHO-COOP committee of principal Investigators [20] (1978) 10627 10627 (100%) 46 Upper third level of cholesterol from 15 745 healthy men 0% 6.4
LEADER study [21,22] (2002) 1568 1568 (100%) 68 lower extremity arterial disease 66% 5.6
E J Whitney [23] (2005) 9795 6138 (63%) 62 Type 2 diabetes mellitus 100% 5.0
FIELD study [24] (2005) 143 132 (92%) 63 Low HDL-C and coronary disease NR 5.1
The ACCORD Study Group [25] (2010) 5518 3824 (69%) 62 Type 2 diabetes mellitus 100% 5.0

Zhou et al.

Zhou et al. BMC Neurology 2013 13:1   doi:10.1186/1471-2377-13-1

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