Table 1

Meta-analysis of neurosurgical clipping vs. endovascular coiling for each outcome
Outcome Studies,n Patients,n Random effects, OR (95% CI) Fixed effects, OR (95% CI) I2,%* HeterogeneityP*
Overall death
 Overall 5 1967 1.42 (0.50, 4.04) 1.42 (0.50, 4.04) 0 0.69
 ≤6 months measurement time 4 1950 1.25 (0.42, 3.74) 1.25 (0.42, 3.74) 0 0.65
In-hospital mortality
 Overall 5 1.55 (0.91, 2.61) 1.35 (1.07, 1.70) 52 0.08
 Adjusted OR 3 3.35 (0.91, 12.30) 3.46 (2.20, 5.44) 83 0.003
Disability (GOS)
 Overall 9 754 2.38 (1.33, 4.26) 2.38 (1.33, 4.26) 0 0.99
 ≤6 months measurement time 4 314 2.72 (1.16, 6.34) 2.72 (1.16, 6.34) 0 0.81
 >6 months measurement time 4 331 2.12 (0.93, 4.84) 2.12 (0.93, 4.84) 0 0.90
 Asian races 4 413 2.41 (1.19, 4.90) 2.41 (1.19, 4.90) 0 0.84
 Western races 5 341 2.32 (0.84, 6.39) 2.32 (0.84, 6.39) 0 0.92
Disability (mRS) 2 262 2.83 (1.42, 5.63) 2.83 (1.42, 5.63) 0 0.81
0 0.72
Complication
 Cerebral haemorrhage 8 7419 1.96 (0.83, 4.64) 1.44 (1.03, 2.02) 63 0.01
 Cerebral infarction 12 7635 1.07 (0.69, 1.66) 0.96 (0.74, 1,23) 39 0.08
 Neurological complication 11 7661 1.94 (1.09-3.47) 1.38 (1.12, 1.71) 58 0.009
 Cardiac complication 6 7067 2.51 (1.15. 5.50) 2.51 (1.15. 5.50) 0 0.98

Abbreviations: OR, odds ratio; CI, confidence interval; mRS, modified Rankin Scale; GOS, Glasgow Outcome Scale; *Values for a random-effects model are reported.

Hwang et al.

Hwang et al. BMC Neurology 2012 12:99   doi:10.1186/1471-2377-12-99

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