Table 1

Clinical characteristics of the study population
All (n=161) Control (n=64) CIND (n=44) Dementia (n=53) p
M/F 90/71 29/35 30/14 31/22 0.06
Age, y 74.4 (7.8) 73.0 (7.0) 73.0 (7.9) 77.1 (8.1) 0.006
Education, y 14.9 (3.2) 15.5 (3.0) 15.4 (3.0) 13.7 (3.3) 0.002
MMSE 26.6 (4.3) 29.2 (1.0) 27.9 (1.7) 22.4 (5.2) <0.001
Depressive score 1.5 (1.7) 0.5 (1.0) 1.8 (0.5) 2.4 (1.9) <0.001
Verbal memory score 88.3 (24.0) 106.7 (15.8) 87.5 (15.3) 62.6 (15.1) <0.001
Visual memory score 86.6 (22.4) 102.9 (12.1) 85.0 (18.3) 61.6 (14.5) <0.001
Executive score 90.8 (18.6) 100.0 (13.8) 90.9 (17.5) 75.2 (16.7) <0.001
Frontal gray matter volume, cm3 200.7 (13.8) 206.7 (12.7) 200.6 (12.4) 193.4 (13.0) <0.001
White matter lesion volume, cm3 19.6 (17.7) 14.0 (6.9) 19.7 (15.6) 26.2 (23.8) <0.001

Mean (standard deviation). All gray matter volumes and WML volume were normalized to total intracranial volume. CIND, Cognitively Impaired Not Demented; MMSE, Mini-Mental State Exam.

Lee et al.

Lee et al. BMC Neurology 2012 12:83   doi:10.1186/1471-2377-12-83

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