Table 2

Prediction performance of various baseline measurements and their combinations in terms of the AUC Score
AUC score
ADAS-cog total 11 0.7024
ADAS-cog total 13 0.7248
ADAS-cog subscore Q1 Word Recall 0.6830
ADAS-cog subscore Q2 Commands 0.1581
ADAS-cog subscore Q3 Construction 0.4899
ADAS-cog subscore Q4 Delayed Word 0.6842
ADAS-cog subscore Q5 Naming 0.3202
ADAS-cog subscore Q6 Ideational 0.5142
ADAS-cog subscore Q7 Orientation 0.4836
ADAS-cog subscore Q8 Word 0.6062
ADAS-cog subscore Q9 Recall 0.2581
ADAS-cog subscore Q10 Spoken 0.3914
ADAS-cog subscore Q11 Word Finding 0.5436
ADAS-cog subscore Q12 Comprehension 0.2756
ADAS-cog subscore Q14 Number Cancellation 0.4451
ADAS-cog subscore Q1-Q14 0.7598
Age 0.5123
Years of Education 0.5090
MMSE Score 0.5916
CDR-SB 0.6064
ADAS total 13 + ADAS subscores 0.7561
ADAS total 13 + ADAS subscores + MMSE + CDR-SB 0.7674
FAQ 0.6874
LDEL: Logical Memory delayed 0.6573
LIMM: Logical Memory immediate 0.6136
MRI (237) 0.7214
Lab tests (18) 0.5348
APOE genotyping 0.5473
TRAA: Trail Making Test: Part A 0.5944
TRAA: Trail Making Test: Part B 0.6187

The numbers in the second column are the leave-one-out AUC score which may be significantly lower than 0.5. The number in the parenthesis denotes the number of measurements involved.

Ye et al.

Ye et al. BMC Neurology 2012 12:46   doi:10.1186/1471-2377-12-46

Open Data