Table 1

Sample characteristics
Non-converter Converter P-Value
Number of subjects 177 (114/64) 142 (87/55)
Age 74.90 ± 7.39 74.49 ± 6.94 0.6150
Years of education 15.65 ± 3.06 15.77 ± 2.90 0.7093
MMSE 27.38 ± 1.75 26.62 ± 1.71 <0.001
CDR-SB 1.37 ± 0.75 1.83 ± 0.93 <0.001
ADAS-cog total 11 9.99 ± 4.16 13.09 ± 4.13 <0.001
ADAS-cog total 13 16.06 ± 6.28 21.12 ± 5.79 <0.001
ADAS-cog subscore Q1 Word Recall 4.07 ± 1.36 5.07 ± 1.23 <0.001
ADAS-cog subscore Q2 Commands 0.14 ± 0.47 0.19 ± 0.44 0.3437
ADAS-cog subscore Q3 0.51 ± 0.54 0.56 ± 0.59 0.3931
ADAS-cog subscore Q4 Delayed Word 5.36 ± 2.33 7.12 ± 1.94 <0.001
ADAS-cog subscore Q5 Naming 0.28 ± 0.52 0.22 ± 0.45 0.2380
ADAS-cog subscore Q6 Ideational 0.14 ± 0.40 0.15 ± 0.45 0.7760
ADAS-cog subscore Q7 Orientation 0.39 ± 0.72 0.93 ± 1.10 <0.001
ADAS-cog subscore Q8 Word 4.05 ± 2.68 5.33 ± 2.52 <0.001
ADAS-cog subscore Q9 Recall 0.06 ± 0.38 0.06 ± 0.26 0.9965
ADAS-cog subscore Q10 Spoken 0.05 ± 0.22 0.13 ± 0.46 0.0517
ADAS-cog subscore Q11 Word Finding 0.24 ± 0.57 0.35 ± 0.63 0.0943
ADAS-cog subscore Q12 0.07 ± 0.33 0.09 ± 0.33 0.5268
ADAS-cog subscore Q14 Number 0.78 ± 0.92 1.08 ± 1.09 0.0101
FAQ: Activities of Daily Living 2.41 ± 3.61 5.37 ± 4.70 <0.001
LDEL: Logical Memory delayed 4.59 ± 2.64 2.81 ± 2.32 <0.001
LIMM: Logical Memory immediate 7.77 ± 3.03 6.46 ± 2.95 <0.001
APOE (0 allele/1 allele/2 alleles) 103/59/15 48/71/23 <0.001
TRAA: Trail Making Test: Part A 40.0 ± 15.5 48.1 ± 25.2 <0.001
TRAA: Trail Making Test: Part B 114.7 ± 64.8 144.0 ± 75.2 <0.001

Ye et al.

Ye et al. BMC Neurology 2012 12:46   doi:10.1186/1471-2377-12-46

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