Table 1

Traumatic brain injury model parameters and stroke model parameters

Traumatic brain injury model parameters

Parameter

Source

Distribution

Parameters


TBI incidence

Entity: TBI

TBI rates (HSU)

Empirical

Barthel index

Assign Barthel group

TBI rates by Barthel index from our study

Dirichlet

Gamma (1,6)

Gamma (1,15)

Gamma (1,36)

Gamma (1,8)

Sex

Assign sex

TBI incidence by sex and age (HSU)

Empirical

Age

Assign age

TBI incidence by sex and age (HSU)

Empirical

Time until death by other causes with

Assign time

Death rates by sex and age (INE)

Gompertz

Men

α = RR*e-9.36

β = 0.085

Women

α = RR*e-12

β = 0.112


Stroke model parameters

Parameter

Source

Distribution

Parameters


Stroke incidence

Entity: Stroke

Stroke rates (HSU)

Empirical

Barthel index for first ever stroke

Assign Barthel group

Barthel Index distribution from our study

Dirichlet

Gamma (1,32)

Gamma (1,44)

Gamma (1,105)

Gamma (1,16)

Sex

Assign sex

Stroke incidence by sex and age (HSU)

Empirical

Age

Assign age

Stroke incidence by sex and age (HSU)

Empirical

Time until death by other causes with

Assign time

Death rates by sex and age (INE)

Gompertz

Men

α = RR*e-9.36

β = 0.085

Women

α = RR*e-12

β = 0.112

Time until recurrent stroke

Assign time

Calibration

Gompertz

Men

α = e-9.0

β = 0.085

Women

α = e-9.7

β = 0.090

Barthel index for recurrent stroke from G0 to

G0

Barthel Index distribution from our study

Dirichlet

Gamma (1,2)

Death

Gamma (1,9)

Barthel index for recurrent stroke from G1 to

G0

Barthel Index distribution from our study

Dirichlet

Gamma (1,5)

G1

Gamma (1,7)

Death

Gamma (1,18)

Barthel index for recurrent stroke from G2 to

G0

Barthel Index distribution from our study

Dirichlet

Gamma (1,7)

G1

Gamma (1,9)

G2

Gamma (1,24)

Death

Gamma (1,16)

Barthel index for recurrent stroke from G3 to

G0

Barthel Index distribution from our study

Dirichlet

Gamma (1,13)

G1

Gamma (1,18)

G2

Gamma (1,48)

G3

Gamma (1,49)

Death

Gamma (1,32)


HSU, Health Statistics Unit in the Spanish Government. ABD, acquired brain damage. INE, Statistics Spanish Institute. RR, relative risk. TBI, Traumatic brain injury. HSU, Health Statistics Unit in the Basque and Navarre Governments. INE, Statistics Spanish Institute. RR, relative risk.

Mar et al. BMC Neurology 2011 11:46   doi:10.1186/1471-2377-11-46

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