Table 2

MOS-SF-36 Quality of Life Domains for Cohorts 1 and 2 (mean [95% confidence intervals]; probability).

Cohort 1

Cohort 2

Domain

HC

n = 295

CFS *

n = 145

HC

n = 19

CFS **

n = 49

CFS+MO**

n = 28

CFS+MA**

n = 12

CFS+T **

n = 9


Physical Functioning

71.6

[67.8-75.4]

47.6

[43.4-52.1]

p < 10-10

91.1

[82.4-99.7]

41.4

[34.6-48.2]

p < 10-10

43.7

[35.5-51.9]

p = 10-9

28.8

[15.6-41.9]

p = 10-8

51.7

[34.5-68.8]

p = 0.0001

Social Functioning

67.4

[63.2-71.6]

46.4

[41.8-51.0]

p = 10-9

87.5

[76.5-98.5]

26.9

[21.0-32.8]

p < 10-10

25.5

[17.9-33.0]

p < 10-10

23.9

[9.3-38.4]

p = 10-7

35.9

[26.2-45.7]

P = 0.000005

Role-Physical

60.5

[63.2-71.6]

18.5

[13.3-23.7]

p < 10-10

76.3

[57.8-94.9]

5.6

[0.8-10.4]

p < 10-10

8.0

[0.5-15.6]

p = 10-9

4.2

[-4.0-12.3]

p = 10-6

0

P = 0.000009

Role-Emotional

71.6

[62.8-80.3]

53.3

[46.2-60.5]

p = 0.008

86.0

[72.5-99.5]

57.6

[44.8-70.5]

59.3

[42.0-76.5]

p = 0.03

55.6

[28.5-82.7]

p = 0.04

55.6

[24.8-86.4]

p = 0.048

Mental Health

66.8

[63.0-70.5]

58.4

[54.9-61.9]

p = 0.006

79.2

[74.0-84.3]

62.6

[57.0-68.3]

64.9

[57.9-71.8]

p = 0.005

59.7

[45.1-74.2]

p = 0.007

59.6

[48.1-71.0]

p = 0.001

Vitality

50.1

[47.1-53.1]

25.4

[22.3-28.5]

p < 10-10

66.1

[56.5-75.8]

13.9

[10.5-17.2]

p < 10-10

14.8

[10.3-19.3]

p < 10-10

6.7

[2.1-11.2]

p = 10-10

20.6

[12.6-28.5]

p = 10-6

Bodily Pain

60.5

[56.5-64.6]

35.1

[31.4-38.8]

p < 10-10

83.8

[72.4-95.2]

34.1

[28.1-40.2]

p < 10-10

32.8

[25.3-40.3]

p = 10-9

30.6

[16.2-44.9]

p = 10-6

42.8

[29.5-56.0]

p = 0.0003

General Health

64.5

[56.5-64.6]

38.3

[34.3-42.3]

p < 10-10

76.8

[69.5-84.2]

33.0

[27.8-38.2]

p < 10-10

36.2

[28.3-44.1]

p = 10-8

28.8

[19.9-37.6]

p = 10-8

29.1

[20.9-37.4]

p = 10-8


2-tailed unpaired Student's t-tests with Bonferroni corrections following ANOVA (p < 0.05): * vs. HC of Cohort 1 and ** vs. HC of Cohort 2.

Ravindran et al. BMC Neurology 2011 11:30   doi:10.1186/1471-2377-11-30

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