Table 2

Interval likelihood ratios for tau and S100B

Marker

Intervala

N (sCJD)b

N (non-CJD)b

iLRc

95% CI


Tau

0-500

5

591

0.06

0.03-0.14

500-1,000

10

138

0.50

0.27-0.92

1,000-3,000

24

65

2.5

1.7-3.9

3,000-10,000

40

27

10.2

6.5-16.0

10,000-∞

41

5

56.4

22.8-140.0

S100B

0-2.0

8

581

0.09

0.05-0.18

2.0-3.0

19

147

0.85

0.55-1.3

3.0-4.0

26

43

4.0

2.5-6.2

4.0-

69

31

14.6

10.0-21.4


a Interval values are in pg/mL for tau, and in ng/mL for S100B.

b Numbers of patients with test results falling into each interval are shown.

c iLR - interval likelihood ratio. Values are estimates of iLR for CSF tau and S100B at illustrative cutoff thresholds.

Coulthart et al. BMC Neurology 2011 11:133   doi:10.1186/1471-2377-11-133

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