Table 2 |
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|
Interval likelihood ratios for tau and S100B |
|||||
|
Marker |
Intervala |
N (sCJD)b |
N (non-CJD)b |
iLRc |
95% CI |
|
|
|||||
|
Tau |
0-500 |
5 |
591 |
0.06 |
0.03-0.14 |
|
500-1,000 |
10 |
138 |
0.50 |
0.27-0.92 |
|
|
1,000-3,000 |
24 |
65 |
2.5 |
1.7-3.9 |
|
|
3,000-10,000 |
40 |
27 |
10.2 |
6.5-16.0 |
|
|
10,000-∞ |
41 |
5 |
56.4 |
22.8-140.0 |
|
|
S100B |
0-2.0 |
8 |
581 |
0.09 |
0.05-0.18 |
|
2.0-3.0 |
19 |
147 |
0.85 |
0.55-1.3 |
|
|
3.0-4.0 |
26 |
43 |
4.0 |
2.5-6.2 |
|
|
4.0-∞ |
69 |
31 |
14.6 |
10.0-21.4 |
|
|
|
|||||
|
a Interval values are in pg/mL for tau, and in ng/mL for S100B. b Numbers of patients with test results falling into each interval are shown. c iLR - interval likelihood ratio. Values are estimates of iLR for CSF tau and S100B at illustrative cutoff thresholds. |
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|
Coulthart et al. BMC Neurology 2011 11:133 doi:10.1186/1471-2377-11-133 |
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