Open Access Research article

Diagnostic accuracy of cerebrospinal fluid protein markers for sporadic Creutzfeldt-Jakob disease in Canada: a 6-year prospective study

Michael B Coulthart1*, Gerard H Jansen23, Elina Olsen2, Deborah L Godal1, Tim Connolly2, Bernard CK Choi456, Zheng Wang2 and Neil R Cashman7

Author Affiliations

1 Canadian Creutzfeldt-Jakob Disease Surveillance System, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg MB R3E 3R2, Canada

2 Canadian Creutzfeldt-Jakob Disease Surveillance System, Public Health Agency of Canada, 200 Églantine Driveway AL 1910B, Ottawa ON K1A 0K9, Canada

3 Department of Pathology and Laboratory Medicine, Eastern Ontario Regional Laboratory, CCW 4240B, The Ottawa Hospital - General Campus, 501 Smyth Rd, Ottawa ON K1H 8L6, Canada

4 Chronic Disease Surveillance and Monitoring Division, CCDPC, HPCDPB, Public Health Agency of Canada, Room 622A3, 785 Carling Avenue, PL# 6806A, Ottawa ON K1A 0K9, Canada

5 Department of Epidemiology and Community Medicine, University of Ottawa, ON, Canada

6 Shantou University Medical College, Shantou, China

7 Brain Research Centre and PrioNet Canada, University of British Columbia, 2011 Wesbrook Mall, Vancouver BC V6T 2B5, Canada

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BMC Neurology 2011, 11:133  doi:10.1186/1471-2377-11-133

Published: 27 October 2011

Additional files

Additional file 1:

Table S1. Specific non-sCJD diagnoses. The table lists the names of specific alternate final diagnoses reached for 543 patients initially suspected to have prion disease, and numbers of cases for each diagnosis.

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