Table 1

Demographic and clinical characteristics among the infarct volume quartile groups

Quartile of DWI lesion volumes, ml

P


Q1

(< 3.1)

n = 58

Q2

(3.1-11.8)

n = 58

Q3

(11.9-44.2)

n = 58

Q4

(> 44.2)

n = 57

(Q4 vs. others)


NISS score on admission

4.0 ± 3.9

8.1 ± 6.1

10.8 ± 6.5

15.1 ± 6.8

< 0.001

Vascular risk factors

Age

69.0 ± 10.9

70.0 ± 11.1

72.5 ± 10.4

69.5 ± 11.7

0.547

Male gender

24(41.4%)

26(44.8%)

32(55.2%)

36(63.2%)

0.036

Hypertension

41(70.7%)

41(70.7%)

42(72.4%)

36(63.2%)

0.250

Diabetes

10(17.2%)

13(22.4%)

7(12.1%)

14(24.6%)

0.222

Previous TIA/stroke

18(31.0%)

15(25.9%)

13(22.4%)

13(22.8%)

0.585

CHADS2*score

0.871

0-1

28(48.3.%)

24(41.4%)

25(43.1%)

25(43.9%)

2-3

22(37.9%)

27(6.6%)

28(48.3%)

24(42.1%)

4-5

8(13.8%)

7(12.1%)

5(8.6%)

8(14.0%)

Dysrhythmia

Paroxysmal atrial fibrillation

22(37.9%)

22(37.9%)

20(34.5%)

18(31.6%)

0.476

Concomitant valvular heart disease

5(8.8%)

9(15.5%)

5(8.6%)

5(8.9%)

0.663

Heart rate (/min)

78.1 ± 19.2

82.9 ± 21.6

85.1 ± 21.4

84.2 ± 23.2

0.480

Medications prior to onset

Antiplatelet agents user

26(45.6%)

20(34.5%)

26(47.3%)

19(33.3%)

0.229

Warfarin user

7(12.1%)

9(15.5%)

4(6.9%)

8(14.0%)

0.610

Laboratory findings

D-dimer, mg/dL

1.51 ± 2.85

2.01 ± 3.31

3.45 ± 12.87

2.06 ± 3.35

0.035

Fibrinogen, mg/dL

320.0 ± 83.9

303.0 ± 79.2

335.5 ± 81.9

346.6 ± 100.2

0.122

C-reactive protein, mg/dL

1.13 ± 2.95

0.69 ± 1.78

0.95 ± 2.04

0.80 ± 1.31

0.068

Prothrombin Time, INR

1.07 ± 0.11

1.10 ± 0.12

1.06 ± 0.11

1.06 ± 0.10

0.373

Transthoracic echocardiogram finding

Left ventricular ejection fraction, %

62.1 ± 9.8

59.7 ± 12.4

60.2 ± 8.5

56.1 ± 15.4

0.020

Left atrium size, ml

48.0 ± 8.8

46.5 ± 9.4

47.8 ± 8.6

46.5 ± 7.2

0.660

E/e' ratio

13.20 ± 6.25

16.76 ± 9.85

13.84 ± 8.06

14.52 ± 9.00

0.839

DT, ms

230.5 ± 153.6

248.3 ± 154.5

207.3 ± 115.8

216.1 ± 114.2

0.925


*In CHADS2, S indicates prior stroke or transient ischemic attack

Oh et al. BMC Neurology 2011 11:107   doi:10.1186/1471-2377-11-107

Open Data