Table 1 |
|||||
|
Results of the evaluation of proteinase K digestion susceptibility. |
|||||
|
Case |
PK treatment |
Mean |
Std. deviation |
Signal reduction (%) |
P value |
|
|
|||||
|
Proband |
No |
1.189 |
0.698 |
79.82 |
<0.0001 |
|
Yes |
0.240 |
0.140 |
|||
|
sCJD MM1 |
No |
3.737 |
0.206 |
22.68 |
0.0041 |
|
Yes |
2.890 |
1.076 |
|||
|
MIE |
No |
0.062 |
0.009 |
4.37 |
0.2740 |
|
Yes |
0.059 |
0.004 |
|||
|
sCJD VV2 |
No |
3.629 |
0.115 |
2.02 |
0.1133 |
|
Yes |
3.556 |
0.152 |
|||
|
|
|||||
|
Proband: The case reported here; sCJD MM1: Sporadic Creutzfeldt-Jakob disease type 1 methionine homozygous at codon 129; sCJD VV2: Sporadic Creutzfeldt-Jakob disease type 2 valine homozygous at codon 129; MIE: A case of multi-infarct encephalopathy used as a negative control |
|||||
|
RodrÃguez-MartÃnez et al. BMC Neurology 2010 10:99 doi:10.1186/1471-2377-10-99 |
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