Table 5

Mean difference in change from baseline in seizure-free days over the last 28 days for pregabalin versus gabapentin from the indirect comparison using placebo as the common comparator

Dose Comparison

Mean Difference

95% CI


150 mg vs. 900 mg

0.97

0.25, 1.69

300 mg vs. 1200 mg

1.24

0.46, 2.02

450 mga vs. 1800 mg

1.35

0.52, 2.18

600 mg vs. 1800 mg

1.48

0.62, 2.34

600 mg vs. 2400 mga

1.42

0.55, 2.29


a450 mg pregabalin and 2400 mg gabapentin were not studied, thus, these results were calculated from the dose-response equation.

Delahoy et al. BMC Neurology 2010 10:104   doi:10.1186/1471-2377-10-104

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