Table 1 |
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|
Dialysis populations: demographics and haematological data. |
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|
Whole population (n-142) |
Multiple myeloma patients (n-41) |
|
|
|
||
|
Male – percentages |
39% |
56% |
|
Ethnicity – percentages |
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|
Caucasian |
85% |
85% |
|
Afro-Caribbean |
4% |
5% |
|
South-Asian |
8% |
10% |
|
Other |
3% |
0% |
|
Median age in years (range) |
70 (19–88) |
67 (38–84) |
|
Median serum creatinine μmol/L (range) |
529 (274–1758) |
622 (302–3000)* |
|
Myeloma type – percentages |
||
|
IgGκ |
24% |
|
|
IgGλ |
22% |
|
|
IgAκ |
7% |
|
|
IgAλ |
15% |
|
|
IgMλ |
2%** |
|
|
Free κ only |
10% |
|
|
Free λ only |
19% |
|
|
κ light chain class (overall) % |
41% |
|
|
|
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|
*Serum creatinine significantly higher in multiple myeloma patients compared with the dialysis population as a whole, P < 0.02. **One patient with known chronic lymphocytic leukaemia, in remission, presented with acute renal failure and biopsy proven cast nephropathy. Investigation identified an intact IgM band on immunofixation electrophoresis with an associated λ FLC, bone marrow examination provided a haematological diagnosis of IgM myeloma. |
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|
Hutchison et al. BMC Nephrology 2008 9:11 doi:10.1186/1471-2369-9-11 |
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