Table 4

Clinical and histologic data at presentation

Responders N = 24

Non responders N = 10

p


I. Clinical


Age (years)

58 ± 16

44 ± 19

0.036

pCreatinine at biopsy (mg/dl)

4.8 ± 2.6

10.2 ± 5.8

0.001

pUrea at biopsy (mg/dl)

105.2 ± 29.8

184 ± 97.5

0.001

CRP (mg/l)

44 ± 49

143 ± 92

<0.0001

ESR (mm/1 h)

112 ± 28

118 ± 47

NS

24 h urinary albumin excretion (g)

1.26 ± 1.1

1.66 ± 0.64

NS


II. Histologic


Crescents (%)

65 ± 32

47 ± 32

NS

Cellular crescents

64 ± 43

49 ± 53

NS

Fibrocellular crescents

8 ± 20

38 ± 52

0.027

Fibrous crescents

12 ± 24

11 ± 2

NS

Obsolete glomeruli

27 ± 20

29 ± 27

NS

Focal necrosis

1.33 ± 0.48

1.60 ± 0.52

NS

TIN infiltration

1.19 ± 1.03

1.22 ± 0.97

NS

Tubular atrophy

0.95 ± 0.72

1.89 ± 1.16

0.011

TIN fibrosis

1.2 ± 0.99

2.22 ± 0.97

0.002

Arterial sclerosis

1.40 ± 1.07

1.67 ± 1.12

0.05


Abbrev: CRP, C-reactive protein, ESR, erythrocyte sedimentation rate, TIN, tubulointerstitial

Alexopoulos et al. BMC Nephrology 2006 7:16   doi:10.1186/1471-2369-7-16

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