Table 4

Performance of the CKD algorithm by age and sex
Sensitivity Specificity PPV NPV
% (95% CI) % (95% CI) % (95% CI) % (95% CI)
66-80 years old 37.6 (36.6-38.6) 97.1 (97.0-97.2) 59.1 (57.9-60.4) 93.3 (93.1-93.5)
>80 years old 28.4 (27.5-29.2) 96.1 (95.8-96.3) 74.5 (73.1-75.8) 76.8 (76.4-77.3)
Code Positive Code Negative
eGFR (mL/min per 1.73m2) Creatinine (μmol/L) eGFR (mL/min per 1.73m2) Creatinine (μmol/L)
66-80 years old 41 (29–55) 133 (104–176) 73 (60–85) 81 (69–95)
>80 years old 34 (25–45) 140 (109–183) 58 (46–72) 87 (71–106)
Sensitivity Specificity PPV NPV
% (95% CI) % (95% CI) % (95% CI) % (95% CI)
Men 43.7 (42.5-44.8) 96.0 (95.8-96.2) 62.0 (60.6-63.3) 91.9 (91.7-92.1)
Women 25.7 (24.9-26.5) 97.6 (97.5-97.7) 69.4 (68.0-70.8) 86.2 (86.0-86.5)
Code Positive Code Negative
eGFR (mL/min per 1.73m2) Creatinine (μmol/L) eGFR (mL/min per 1.73m2) Creatinine (μmol/L)
Men 40 (28–53) 145 (115–190) 72 (59–83) 90 (79–106)
Women 36 (25–49) 123 (95–164) 67 (53–81) 74 (64–89)

Abbreviations: ICD-10, International Classification of Diseases, 10th revision; OHIP, Ontario Health Insurance Plan; PPV, positive predictive value; NPV, negative predictive value; CI, confidence interval.

Dichotomous results are presented for a reference eGFR < 45 mL/min per 1.73 m2.

Numbers listed are median (interquartile range).

Creatinine was measured in serum.

Fleet et al.

Fleet et al. BMC Nephrology 2013 14:81   doi:10.1186/1471-2369-14-81

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