Table 2

Comparison of various parameters in glomerular filtration stages of chronic kidney disease in type 2 diabetes patients (n=182)
G1 G2 G3 G4 Total Jonckheere-Terpstra
Number (male/female) 37 (21 / 16) 99 (37 / 62) 41 (12 / 29) 5 (1 / 4) 182 (71 / 111) 0.009**
Age (years) 50.0±15.5 60.7±10.8 70.2±11.7 73.8±7.8 60.4±14.4 6.43×10-10**
BMI (kg/m2) 27.0±6.9 25.5±4.8 24.7±4.0 25.9±1.7 25.6±5.1 0.242
SBP (mmHg) 128.9±14.7 129.7±15.4 129.6±18.3 128.2±18.4 129.5±15.9 0.939
DBP (mmHg) 77.7±10.8 74.5±10.9 73.1±12.9 67.4±9.8 74.7±11.4 0.031*
PG (mmol/L) 9.6±4.2 8.6±3.1 8.8±3.1 8.6±3.1 8.9±3.3 0.113
HbA1c (%) 7.90±1.54 7.25±1.01 7.13±0.78 7.04±0.88 7.35±1.12 0.029*
HbA1c (mmol/mol) 65.3±16.0 58.5±10.5 57.3±8.1 73.1±9.1 76.4±11.6 0.029*
ACR (mg/gCr) 19.6±27.7 130.6±344.4 421.4±1191 702.1±603.0 196.6±655.0 0.005**
Cr (μmol/L) 49.5±8.8 66.3±11.5 94.6±23.0 245.8±114.9 74.3±39.8 3.45×10-21**
UN (mmol/L) 4.7±1.6 5.7±1.6 20.6±7.4 15.7±2.1 6.1±2.5 1.60×10-9**
eGFR (mL/s) 1.76±0.26 1.25±0.14 0.85±0.13 0.33±0.10 1.24±0.37 8.80×10-30**
Osmotic pressure (mmol/kg) 299.3±4.0 301.2±4.3 303.0±4.2 312.9±1.2 301.6±4.8 4.78×10-6**
T-Cho (mmol/L) 4.77±0.81 4.93±0.88 4.80±1.30 5.05±0.90 4.87±0.97 0.736
TG (mmol/L) 1.51±0.74 1.51±0.77 1.68±0.91 2.19±1.16 1.56±0.81 0.391
HDL-C (mmol/L) 1.48±0.36 1.61±0.54 1.53±0.45 1.27±0.06 1.56±0.49 0.776
LDL-C (mmol/L) 2.67±0.70 2.79±0.68 2.73±0.80 3.09±0.99 2.75±0.72 0.753
Log10Gal-9 (pg/mL) 1.89±0.41 1.94±0.42 2.02±0.43 2.27±0.32 1.96±0.42 0.012*

BMI, body mass index; SBP, Systolic Blood Pressure; DPB, Diastolic Blood Pressure; PG, Plasma glucose; ACR, albumin / creatinine ratio; Cr, serum creatinine; UN, serum urea nitrogen; eGFR, estimated glomerular filtration ratio; T-Cho, Total cholesterol; TG, Triglyceride; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; Log10Gal-9, Log10galectin-9 (pg/mL). *, p < 0.05; **, p < 0.01.

Kurose et al.

Kurose et al. BMC Nephrology 2013 14:23   doi:10.1186/1471-2369-14-23

Open Data