Additional file 4.

Repeated measurements of NAG/Cr could not predict renal function deterioration in 1 year. The patients were divided into three groups according to serial measurements of urinary NAG/Cr: persistently low NAG/Cr (<4.95 IU/g) (Group L-L), variable NAG/Cr (Group V), and persistently high NAG/Cr (≥4.95 IU/g) (Group H-H). Group H-H showed lower estimated GFRs at baseline (64.5 ± 23.3 mL/min/1.73 m2) and lower estimated GFR at 12 month (50.3 ± 18.5 mL/min/1.73 m2) compared to other groups (P < 0.001). Although statistically insignificant, the percentage decrement of estimated GFR over 12 months were greater in Group H-H compared to the other groups (Group H-H vs. Group V vs. Group L-L, -23.0% vs. -20.8% vs. -21.2%, P = 0.77).

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Park et al. BMC Nephrology 2012 13:93   doi:10.1186/1471-2369-13-93