Receiver operating characteristic curve analysis with urinary biomarkers for estimated GFR < 60 mL/min/1.73 m2(A) and TKV > 1000 mL (B). Urinary NAG/Cr is a better marker for discriminating patients with decreased estimated GFRs (< 60 mL/min/1.73 m2) from those with conserved renal function, showing the largest AUC (0.794). In addition, urinary NAG/Cr can best discriminate patients with enlarged TKV (>1000 mL), showing an AUC of 0.637.
Park et al. BMC Nephrology 2012 13:93 doi:10.1186/1471-2369-13-93