Representative photomicrographs of kidneys from Pax8-rtTA/LC1/floxed ETA (iETA) mice before and after doxycycline (DOX) treatment. Panel A shows cortex and Panel B shows medulla prior to DOX treatment; Panel C shows cortex after DOX treatment. DOX-treated iETA medullary staining is not shown since ETA immunostaining was not apparent in untreated iETA mice. Arrows indicate blood vessels. Staining was performed on 6 different mice of each genotype. Images are 200X.
Stuart et al. BMC Nephrology 2012 13:166 doi:10.1186/1471-2369-13-166