Table 1

Characteristics of all patients with ESKD secondary to HUS or other causes in Australia and New Zealand 1963–2010, before and after matching for age, gender and RRT era
Before matching After matching
Characteristic HUS ESKD (n = 241) Other ESKD (n = 58181) P value Other ESKD Control (n = 241) P value
Age 33.1 ± 21.8 54.2 ± 17.3 <0.001 33.1 ± 21.7 1.00
Age category <0.001 1.00
0-9 years 43 (18%) 529 (1%) 43 (18%)
  10-19 years 28 (12%) 1607 (3%) 28 (12%)
20-29 years 46 (19%) 3978 (7%) 46 (19%)
30-39 years 32 (13%) 5772 (10%) 32 (13%)
40-49 years 31 (13%) 9122 (16%) 31 (13%)
50-59 years 25 (10%) 12339 (21%) 25 (10%)
60-69 years 21 (9%) 12866 (22%) 21 (9%)
70-79 years 13 (5%) 9741 (17%) 13 (5%)
80+ years 2 (1%) 2327 (4%) 2 (1%)
Male gender 90 (37%) 33913 (58%) <0.001 90 (37%) 1.00
Racial origin <0.001 <0.001
  European 217 (90%) 45368 (78%) 170 (71%)
  ATSI 4 (2%) 3484 (6%) 22 (9%)
  MPI 8 (3%) 5106 (9%) 24 (10%)
  Asian 6 (3%) 2478 (4%) 9 (4%)
  Other 6 (3%) 1745 (3%) 16 (7%)
RRT era 0.17 1.00
 1963-1975 13 (5%) 2821 (5%) 12 (5%)
 1976-1985 36 (15%) 6505 (11%) 36 (15%)
 1986-1995 44 (18%) 12119 (21%) 45 (19%)
 1996-2000 50 (21%) 9811 (17%) 49 (20%)
 2001-2005 44 (18%) 12357 (21%) 45 (19%)
 2006-2010 54 (22%) 14568 (25%) 54 (22%)
Ever smoked <0.001 0.85
Current 28 (12%) 6138 (11%) 31 (13%)
Former 42 (17%) 17713 (30%) 48 (20%)
Never 130 (54%) 22398 (39%) 122 (51%)
Missing 41 (17%) 11932 (21%) 40 (17%)
Hypertension <0.001 0.98
 Yes 89 (37%) 24464 (42%) 87 (36%)
 No 37 (15%) 4519 (8%) 38 (16%)
 Missing 115 (48%) 29198 (50%) 116 (48%)
Diabetes mellitus <0.001 <0.001
  Yes 8 (3%) 17874 (31%) 51 (21%)
  No 201 (83%) 31796 (55%) 163 (68%)
  Missing 32 (13%) 8511 (15%) 27 (11%)
Chronic lung disease 0.009 0.47
  Yes 16 (7%) 7139 (12%) 22 (9%)
  No 190 (79%) 41125 (71%) 190 (79%)
  Missing 35 (15%) 9917 (17%) 29 (12%)
Coronary artery disease <0.001 0.13
  Yes 22 (9%) 17613(30%) 36 (15%)
  No 184 (76%) 30768 (53%) 176 (7%)
  Missing 35 (15%) 9800 (17%) 29 (12%)
Peripheral vascular disease <0.001 0.04
  Yes 15 (6%) 11440 (20%) 31 (13%)
  No 191 (79%) 36823 (63%) 181 (75%)
  Missing 35 (15%) 9918 (17%) 29 (12%)
Cerebrovascular disease 0.01 0.38
  Yes 14 (6%) 6540 (11%) 9 (4%)
  No 192 (80%) 41742 (72%) 204 (84%)
  Missing 35 (15%) 9899 (17%) 29 (12%)
BMI (kg/m2) 22.7 ± 6.2 26.6 ± 6.3 <0.001 24.5 ± 7.7 0.02
Late referral <0.001 <0.001
  Yes 88 (37%) 9304 (16%) 34 (14%)
  No 86 (36%) 33773 (58%) 156 (65%)
  Missing 67 (28%) 15104 (26%) 51 (21%)
Renal Biopsy <0.001 <0.001
  Yes 89 (37%) 16019 (28%) 85 (35%)
  No 61 (25%) 29135 (50%) 117 (49%)
  Miss 91 (38%) 13027 (22%) 39 (16%)
First RRT 0.46 0.02
  Haemodialysis 163 (68%) 39135 (67%) 134 (56%)
  Peritoneal dialysis 69 (29%) 17570 (30%) 92 (38%)
  Renal Transplant 9 (4%) 1476 (3%) 15 (6%)
RRT duration (years) 4.7 [1.6-11.8] 3.8 [1.6-8.3] 0.03 6.4 [2.3-14.3] 0.03

Abbreviations: ATSI Aboriginal and Torres Strait Islander, BMI Body mass index, MPI Maori and Pacific Islander, RRT Renal replacement therapy.

Tang et al.

Tang et al. BMC Nephrology 2012 13:164   doi:10.1186/1471-2369-13-164

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