Table 1

Characteristics of patients at baseline
Number of patients 58 (100%)
Age 49 [23–89]
Male 49 (68.9%)
Blood pressure (mmHg)
Systolic 130 (88–181)
Diastolic 78 (59–115)
Pulse pressure 50 (28–80)
Renal function
 Serum creatinine (μmol/L) 124 (54–906)
 eGFR (ml/min/1,73m2) 59 (5–130)
 Proteinuria/creatininuria(mg/mmol) 245 (7–2000)
Antihypertensive treatments
 No antihypertensive drug 27 (46.5%)
 1 antihypertensive drug 11 (19%)
 2 antihypertensive drugs 9 (15.5%)
 ≥ 3 antihypertensive drugs 11 (19%)
 RAS blockers 23 (39.6%)
Renal biopsy
 % sclerotic glomeruli 13 (0–96)
 % interstitial fibrosis 10 (0–90)
 Vascular lesions 34/51 (66.7%)
 Arteriolar hyaline deposits 25/53 (47.2%)
 Intima/media ratio
  Normal 25 (54.4%)
  < 1 13 (28.3%)
  ≥ 1 8 (17.3%)
Diagnosis
 FSGN/HIVAN 9 (15.5%)
 IgA nephropathy 11 (19%)
 Membranous nephropathy 7 (12.1%)
 Minimal change disease 3 (5.2%)
 Lupus 3 (5.2%)
 Vascularitis 3 (5.2%)
 Membranous proliferative nephritis 2 (3.4%)
 Diabetes 2 (3.4%)
 Amyloidosis 2 (3.4%)
 Other glomerulonephritis 5 (8.6%)
 Acute tubulo-interstitial nephritis 3 (1.7%)
 Chronic tubulo-interstitial nephritis 2 (3.4%)
 Vascular nephropathy 2 (3.4%)
 Other 4 (6.9%)
Renal arterial resistive index 0.62 (0.31-1.00)

Bigé et al.

Bigé et al. BMC Nephrology 2012 13:139   doi:10.1186/1471-2369-13-139

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