Table 3

Correlations among the measured parameters in CKD patients at before- and after-dialysis settings
Parameters Duration Lactate Pyruvate Lactate/Pyruvate ratio HIF-1α VEGF TAC Total peroxides
Lactate
Before dialysis −0.208(0.197)
After dialysis −0.184(0.256)
Pyruvate
Before dialysis −0.193(0.234) 0.282(0.078)
After dialysis −0.095(0.580) 0.533(0.001)
Lactate/pyruvate ratio
Before dialysis −0.067(0.640) 0.513(0.001) −0.457(0.003)
After dialysis −0.037(0.824) 0.212(0.188) −0.630(0.001)
HIF-1α
Before dialysis 0.677 (0.001) 0.125(0.442) −0.149(0.359) 0.220(0.173)
After dialysis −0.186(0.249) 0.048(0.770) 0.015(0.929) 0.229(0.156)
VEGF
Before dialysis −0.486(0.001) 0.291(0.069) 0.316(0.047) 0.027(0.866) 0.374(0.018)
After dialysis 0.189 (0.243) 0.125 (0.441) 0.059(0718) 0.098(0.545) −0.163(0.314)
TAC
Before dialysis 0.265 (0.098) −0.174(0.283) −0.147(0.366) −0.142(0.384) 0.068(0.676) −0.206(0.202)
After dialysis 0.022 (0.894) 0.048(0.771) −0.148(0.361) 0.105(0.517) −0.220(0.173) −0147(0.366)
Total peroxides
Before dialysis −0.017(0.918) −0.032(0.843) −0.194(0.230) 0.128(0.430) −0.138(0.394) 0.229(0.156) −0.247(0.124)
After dialysis 0.283 (0.077) 0.036(0.825) 0.070(0.668) −0.204(0.207) −0.529(0.001) −0.006(0.972) 0.168(0.301)
Oxidative stress index
Before dialysis −0.093(0.566) −0.002(0.989) 0.161(0.322) 0.156(0.337) −0.172(0.287) 0.245(0.128) −0.469(0.002) 0.969(0.001)
After dialysis 0.285 (0.075) 0.015(0.929) 0.113(0.489) −0.240(0.136) −0.459(0.003) 0.062(0.705) −0.155(0.340) 0.944(0.001)

Data shown are r value (P< value). HIF-1α= hypoxia induced factor-1α, VEGF= vascular endothelial growth factor. TAC = total antioxidant capacity.

Hamed et al.

Hamed et al. BMC Nephrology 2012 13:136   doi:10.1186/1471-2369-13-136

Open Data