Table 3 |
||||||||
| Correlations among the measured parameters in CKD patients at before- and after-dialysis settings | ||||||||
| Parameters | Duration | Lactate | Pyruvate | Lactate/Pyruvate ratio | HIF-1α | VEGF | TAC | Total peroxides |
| Lactate | ||||||||
| Before dialysis | −0.208(0.197) | |||||||
| After dialysis | −0.184(0.256) | |||||||
| Pyruvate | ||||||||
| Before dialysis | −0.193(0.234) | 0.282(0.078) | ||||||
| After dialysis | −0.095(0.580) | 0.533(0.001) | ||||||
| Lactate/pyruvate ratio | ||||||||
| Before dialysis | −0.067(0.640) | 0.513(0.001) | −0.457(0.003) | |||||
| After dialysis | −0.037(0.824) | 0.212(0.188) | −0.630(0.001) | |||||
| HIF-1α | ||||||||
| Before dialysis | 0.677 (0.001) | 0.125(0.442) | −0.149(0.359) | 0.220(0.173) | ||||
| After dialysis | −0.186(0.249) | 0.048(0.770) | 0.015(0.929) | 0.229(0.156) | ||||
| VEGF | ||||||||
| Before dialysis | −0.486(0.001) | 0.291(0.069) | 0.316(0.047) | 0.027(0.866) | 0.374(0.018) | |||
| After dialysis | 0.189 (0.243) | 0.125 (0.441) | 0.059(0718) | 0.098(0.545) | −0.163(0.314) | |||
| TAC | ||||||||
| Before dialysis | 0.265 (0.098) | −0.174(0.283) | −0.147(0.366) | −0.142(0.384) | 0.068(0.676) | −0.206(0.202) | ||
| After dialysis | 0.022 (0.894) | 0.048(0.771) | −0.148(0.361) | 0.105(0.517) | −0.220(0.173) | −0147(0.366) | ||
| Total peroxides | ||||||||
| Before dialysis | −0.017(0.918) | −0.032(0.843) | −0.194(0.230) | 0.128(0.430) | −0.138(0.394) | 0.229(0.156) | −0.247(0.124) | |
| After dialysis | 0.283 (0.077) | 0.036(0.825) | 0.070(0.668) | −0.204(0.207) | −0.529(0.001) | −0.006(0.972) | 0.168(0.301) | |
| Oxidative stress index | ||||||||
| Before dialysis | −0.093(0.566) | −0.002(0.989) | 0.161(0.322) | 0.156(0.337) | −0.172(0.287) | 0.245(0.128) | −0.469(0.002) | 0.969(0.001) |
| After dialysis | 0.285 (0.075) | 0.015(0.929) | 0.113(0.489) | −0.240(0.136) | −0.459(0.003) | 0.062(0.705) | −0.155(0.340) | 0.944(0.001) |
Data shown are r value (P< value). HIF-1α= hypoxia induced factor-1α, VEGF= vascular endothelial growth factor. TAC = total antioxidant capacity.
Hamed et al. BMC Nephrology 2012 13:136 doi:10.1186/1471-2369-13-136
