Table 2

Results platelet activation
Controls CKD P-value P-value
N = 19 N = 23 Adjusted for age
Maximal MFI TRAP, AU (IQR) 11.4 (9.2-12.2) 9.7 (7.9-10.8) 0.032 0.095
Maximal MFI ADP, AU (IQR) 2.6 (1.9-3.5) 1.6 (1.2-2.1) 0.002 0.004
Maximal MFICRP, AU (IQR) 11.5 (9.5-12.9) 9.2 (8.5-10.8) 0.004 0.010
EC50 TRAP, μM (IQR) 1.9 (1.5-2.5) 2.3 (1.8-2.6) 0.372 0.182
EC50 ADP, μM (IQR) 0.9 (0.6-1.1) 0.89 (0.7-1.1) 0.544 0.597
EC50 CRP, ng/ml (IQR) 120 (46.7-312.7) 116.1 (46.1-270.5) 0.955 0.660
AUC TRAP, AU (IQR) 47.1 (41.1-54.2) 39.5 (32.9-44.4) 0.012 0.023
AUC ADP, AU (IQR) 8.9 (7.9-12.2) 5.8 (3.8-7.3) 0.002 0.003
AUC CRP, AU (IQR) 30.3 (22.1-41.9) 23.4 (18.9-34.7) 0.063 0.322

MFI Mean fluorescence intensity, AU arbitrary units, IQR inter quartile range, EC50 concentration of agonist leading to a half maximal P-selectin expression, AUC Area under the curve.

van Bladel et al.

van Bladel et al. BMC Nephrology 2012 13:127   doi:10.1186/1471-2369-13-127

Open Data