Table 5

Hazard ratio of recurrent cardiovascular event or death in ADVANCE cohort by eGFR (ml/min/1.73 m2)*

Hazard ratio (95% CI) of recurrent cardiovascular event or death


Model 1: Unadjusted Model


eGFR > 60

Referent


eGFR 45-59

1.61 (1.18 to 2.18)


eGFR < 45

1.85 (1.19 to 2.89)


Model 2: Adjusted for age, sex, race/ethnicity, smoking, alcohol use, and physical activity


eGFR > 60

Referent


eGFR 45-59

1.52 (1.11 to 2.10)


eGFR < 45

1.70 (1.10 to 2.67)


Model 3: Model 2 + adjusted for body mass index and history of diabetes and hypertension


eGFR > 60

Referent


eGFR 45-59

1.47 (1.10 to 2.02)


eGFR < 45

1.58 (1.00 to 2.50)


Model 4: Model 3 + medication possession ratio of statins, β-blockers, calcium channel blockers, ACE inhibitors/ARBs


eGFR > 60

Referent


eGFR 45-59

0.82 (0.25 to 2.66)


eGFR < 45

1.19 (0.25 to 5.58)


*eGFR indicates glomerular filtration rate

†ACE inhibitor indicates angiotensin converting enzyme inhibitor

‡ARB indicates angiotensin receptor blocker

Bansal et al. BMC Nephrology 2011 12:44   doi:10.1186/1471-2369-12-44

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