Table 1

Baseline characteristics of ADVANCE subjects with incident coronary heart disease at enrollment by CKD status*

Characteristic

CKD

(N = 159)

Non-CKD

(N = 1088)

P Value


Mean (SD) Age, year

66.8 (7.9)

61.7 (8.3)

< 0.001


Women, %

42.8

25

< 0.001


African American

6.3

3.9


Mean (SD) prior estimated glomerular filtration rate (ml/min/1.73 m2)

49.7 (9.8)

85 (17.7)

< 0.001


Married/Domestic Partner

66.7

75.1

< 0.001


Current cigarette smoking, %

7.6

9.0

0.3


Alcohol use in prior 12 months, %

67.3

69.8

0.5


Leisure-time Activity in past 12 months, %

0.02


Minimal

42.8

31.0


Light

12.6

18.9


Moderate

31.5

35.8


Heavy

13.2

14.3


Medical History, %


Stroke/transient ischemic attack

17.0

9.4

< 0.001


Peripheral arterial disease

13.8

9.4

0.08


Diabetes mellitus

34.6

26.9

0.04


Diagnosed hypertension

90.6

79.5

< 0.001


Parental History of Coronary Disease, %

45.9

51.4

0.2


Sibling History of Coronary Disease, %

25.8

22.9

0.4


Mean systolic blood pressure (mm Hg)

132.0

122.0

< 0.001


Systolic (mm Hg), %

< 0.001


≤ 120

31.7

52.2


121-129

19.0

18.7


130-139

16.5

13.1


140-159

19.0

12.3


160-179

11.4

2.8


> 180

2.5

1.0


Mean diastolic blood pressure (mm Hg)

73.0

71.1

0.02


Diastolic (mmHg), %

< 0.001


≤ 80

81.5

84.7


81-84

6.4

8.5


85-89

4.5

4.1


90-99

4.5

2.6


100-109

1.9

0.2


≥ 110

1.3

0


Mean (SD) total cholesterol

215.2 (41.4)

214.9 (41.8)

0.9


Mean (SD) LDL cholesterol

126.9 (32.8)

131.7 (35.7)

0.2


Mean (SD) HDL cholesterol

47.2 (14.4)

44.5 (12.2)

0.02


Mean (SD) triglyceride level

201.2 (139.0)

200.4 (130.2)

0.9


Mean (SD) body mass index (kg/m2)

29.6 (5.1)

29.1 (5.4)

0.4


*CKD indicates chronic kidney disease

Bansal et al. BMC Nephrology 2011 12:44   doi:10.1186/1471-2369-12-44

Open Data