Table 6 |
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|
Coagulation parameters. |
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|
Acetate (A) |
Citrate (C) |
P(A vs.C) |
P (pre-post) |
||
|
|
|||||
|
Whole group |
|||||
|
TAT, ug/l |
pre-dialysis |
4.34 ± 1.90 |
4.52 ± 3.29 |
ns |
A < 0.05 |
|
post-dialysis |
7.05 ± 6.14 |
7.76 ± 8.97 |
ns |
C ns |
|
|
F1+2, pmol/l |
pre-dialysis |
275 ± 200 |
252 ± 183 |
ns |
A ns |
|
post-dialysis |
277 ± 230 |
278 ± 281 |
ns |
C ns |
|
|
Patients with a more pronounced coagulation activation (doubling or more of the pre-dialysis TAT); n = 7; post-hoc analysis |
|||||
|
TAT, ug/l |
pre-dialysis |
5.22 ± 2.22 |
4.28 ± 1.19 |
ns |
A < 0.01 |
|
post-dialysis |
14.9 ± 6.78 |
17.0 ± 13.34 |
ns |
C < 0.01 |
|
|
F1+2, pmol/l |
pre-dialysis |
403 ± 181 |
374 ± 228 |
ns |
A < 0.05 |
|
post-dialysis |
560 ± 194 |
577 ± 391 |
ns |
C < 0.05 |
|
|
|
|||||
|
Pre- and post-dialysis thrombin-antithrombin complexes (TAT) and prothrombin fragments 1+2 (F1+2) using acetate dialysate (A) vs. citrate (C) dialysate without calcium supplementation. |
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|
Gabutti et al. BMC Nephrology 2009 10:7 doi:10.1186/1471-2369-10-7 |
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