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Association of SREBP-2 haplotypes between the AVN patients and controls |
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| Haplotype |
Genotype |
Controls (%) |
Patients (%) |
Codominant |
Dominant |
Recessive |
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|
|
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| OR (95% CI) |
P* |
OR (95% CI) |
P* |
OR (95% CI) |
P* |
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|
|
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| ht1 |
ht1/ht1 |
51 (19.03) |
73 (16.67) |
0.78 (0.624–0.975) |
0.029 |
0.672 (0.481–0.94) |
0.020 |
0.799 (0.536–1.192) |
0.272 |
| (G-G) |
ht1/- |
143 (53.36) |
209 (47.72) |
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| -/- |
74 (27.61) |
156 (35.62) |
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| ht2 |
h2/ht2 |
15 (5.6) |
53 (12.1) |
1.245 (0.981–1.581) |
0.071 |
1.128 (0.83–1.534) |
0.440 |
2.238 (1.231–4.069) |
0.008 |
| (G-A) |
ht2/- |
122 (45.52) 131 (48.88) |
184 (42.01) 201 (45.89) |
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| ht3 |
ht3/ht3 |
16 (5.97) |
31 (7.08) |
1.081 (0.842–1.388) |
0.542 |
1.068 (0.783–1.456) |
0.678 |
1.245 (0.663–2.336) |
0.495 |
| (T-G) |
ht3/- |
105 (39.18) |
168 (38.36) |
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| -/- |
147 (54.85) |
239 (54.57) |
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|
Haplotypes; rs2269657, rs1052717 *Logistic regression analyses were used for calculating. bold: P value < 0.05 | |||||||||
Kim et al. BMC Medical Genetics 2008 9:94 doi:10.1186/1471-2350-9-94 |
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