|
Description of TLR4 variants genotyped (n = 1,968). |
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| SNP number |
dbSNP identifier |
Exchange |
Genotype frequenciesa |
Gene location |
||
|
|
||||||
| (1 > 2) |
11 |
12 |
22 |
|||
|
|
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| 1 |
rs2770150 |
T > C |
52.6 |
40.1 |
7.3 |
5'Upstream |
| 2 |
rs6478317 |
A > G |
46.5 |
42.7 |
10.8 |
5'Upstream |
| 3 |
rs1927911 |
C > T |
57.6 |
35.7 |
6.7 |
Intronic |
| 4 |
rs2149356 |
C > A |
47.7 |
42.2 |
10.1 |
Intronic, TFBS |
| 5 |
rs4986791 |
C > T |
88.1 |
11.6 |
0.3 |
Ile399Thr, HMCS |
| 6 |
rs7873784 |
G > C |
74.2 |
23.4 |
2.4 |
3'Untranslated region |
| 7 |
rs1927906 |
A > G |
81.3 |
18 |
0.8 |
3'Flanking |
|
aweighted due to the sampling schene; TFBS: Transcription factor binding site; HMCS: human-mouse conserved segments | ||||||
Kolz et al. BMC Medical Genetics 2008 9:9 doi:10.1186/1471-2350-9-9 |
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