Table 6

Allele frequency distribution and association study in ADAM33

Name

SNP

Minor allele frequency

P-value

Permutation p-value

Odds ratio (95% CI)

AR (n = 128)

AS (n = 181)

CTR (n = 151)

AR vs CTR

AS vs CTR

AR vs CTR

AS vs CTR

AR vs CTR

AS vs CTR

Rs2787094

G/C

0.406

0.514

0.146

<0.0001

<0.0001

<0.0001

<0.0001

0.25(0.17–0.37)

0.16(0.11–0.24)

rs2280089

A/G

0.231

0.102

0.136

0.0037

0.1812

0.0279

1.91(1.23–2.96)

rs2280090

A/G

0.094

0.158

0.04

0.0097

<0.0001

<0.0001

4.52(2.37–8.59)

rs2280091

G/A

0.348

0.437

0.129

<0.0001

<0.0001

<0.0001

<0.0001

0.28(0.18–0.42)

0.19(0.13–0.28)

rs3918396

G/A

0.109

0.113

0.136

0.3454

0.3802

rs612709

A/G

0.063

0.121

0.036

0.1526

<0.0001

0.0016

3.66(1.86–7.22)

Su et al. BMC Medical Genetics 2008 9:82   doi:10.1186/1471-2350-9-82