Table 4 |
||||
|
Power of genotype association statistics given as 1-β error probability. The β represents the probability of falsely accepting H0 hypothesis (lack of association) when in fact H1 hypothesis (association) is true. |
||||
|
Polymorphism |
Genet. model |
CD |
PSC |
PBC |
|
|
||||
|
NOD2/CARD15 Pro268Ser |
dominant |
0.59 |
0.04 |
<0.01 |
|
recessive |
0.98 |
0.03 |
0.04 |
|
|
NOD2/CARD15 Arg702Trp |
dominant |
0.71 |
0.11 |
0.08 |
|
recessive |
n/a |
<0.01 |
n/a |
|
|
NOD2/CARD15 Gly908Arg |
dominant |
<0.01 |
<0.01 |
0.05 |
|
recessive |
n/a |
n/a |
n/a |
|
|
NOD2/CARD15 1007fs |
dominant |
0.99 |
0.02 |
0.01 |
|
recessive |
0.86 |
<0.01 |
n/a |
|
|
OCTN1 Leu503Phe |
dominant |
0.08 |
<0.01 |
<0.01 |
|
recessive |
0.04 |
0.02 |
0.02 |
|
|
OCTN2-207G>C |
dominant |
<0.01 |
<0.01 |
0.01 |
|
recessive |
<0.01 |
0.09 |
<0.01 |
|
|
DLG5 Arg30Gln |
dominant |
<0.01 |
0.02 |
0.01 |
|
recessive |
<0.01 |
0.02 |
<0.01 |
|
|
IL23R Arg381Gln |
dominant |
<0.01 |
0.08 |
0.03 |
|
recessive |
<0.01 |
<0.01 |
n/a |
|
|
IL23R His3Gln |
dominant |
0.09 |
0.01 |
0.06 |
|
recessive |
<0.01 |
0.02 |
<0.01 |
|
|
IL23R exon-3'UTR |
dominant |
0.05 |
0.01 |
0.01 |
|
recessive |
<0.01 |
0.01 |
<0.01 |
|
|
ATG16L1 Thr300Ala |
dominant |
0.32 |
0.04 |
0.01 |
|
recessive |
0.05 |
0.04 |
0.02 |
|
|
|
||||
|
Gaj et al. BMC Medical Genetics 2008 9:81 doi:10.1186/1471-2350-9-81 |
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