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HLA-DQB1 distribution in Mexican Mestizo DQB1*0602 negative patients and controls. |
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| Locus |
Patients |
Controls |
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| DQB1* |
ΛN = 11 |
AF% |
ςN = 181 |
AF% |
X2Y |
OR |
(CI) |
p |
pc |
|
|
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| 0201 |
4 |
18.2 |
38 |
10.5 |
0.6 |
||||
| 0301 |
11** |
50 |
97 |
26.8 |
4.4 |
2.7 |
(1.1–6.5) |
0.035 |
NS |
| 0302 |
3 |
13.6 |
104 |
28.7 |
1.7 |
||||
| 0303 |
0 |
0 |
5 |
1.4 |
0.2 |
||||
| 0402 |
2 |
9.1 |
55 |
15.2 |
0.2 |
||||
| 0501 |
1 |
4.5 |
33 |
9.1 |
0.1 |
||||
| 0502 |
0 |
0 |
5 |
1.4 |
0.2 |
||||
| 0503 |
0 |
0 |
5 |
1.4 |
0.2 |
||||
| 0601 |
0 |
0 |
4 |
1.1 |
0.3 |
||||
| 0603 |
0 |
0 |
7 |
1.9 |
0 |
||||
| 0604 |
0 |
0 |
7 |
1.9 |
0 |
||||
| 0605 |
1 |
4.5 |
1 |
0.3 |
1.4 |
||||
| 0609 |
0 |
0 |
1 |
0.3 |
1.4 |
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|
AF: allele frequency; X2Y: Chi2 value with Yates correction; OR: Odds Ratio; CI: Confidence Interval; pc: Bonferroni correction (the p value was multiplied by the total number of alleles tested); NS: Not significant; Λ: 11/32 total patients were DQB1*0602 negative; ς: 181/203 total controls were DQB1*0602 negative. ** this number includes two DQB1*0301 homozygotes. | |||||||||
Alaez et al. BMC Medical Genetics 2008 9:79 doi:10.1186/1471-2350-9-79 |
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