Table 3

Other studies showing genetic effects on fibrinogen levels.

Variant, and/or locus

Physical locus

LOD score or p-value

Reference

Chromo 1p31.3 rs6683832

62,988,925

5.6 × 10^-5

Yang et al [41]

1p31 Leptin receptor (LEPR) haplotype block including: rs3790432, rs1137101, rs1805096

65,764,013 – 65,873,699

0.005

Zhang et al [45]

Chromo 2, 55.5 cM (African Americans)

36,013,772 – 36,214,030

LOD = 2.14

Ding et al [41]

Chromo 2, q36.3 rs1273819

227,307,918

LOD = 2.4

Yang et al [41]

Chromo 6, 136 cM (African Americans)

134,596,514 – 134,796,754

LOD = 1.43

Ding et al [41]

Chromo 12, 152.16 cM fibrinogen and CRP (bivariate) (African Americans)

127,228,944 – 127,429,321

LOD = 3.44

Ding et al [41]

Chromo 12q14.2 rs10506540

65,699,364

2.2 × 10^-5

Yang et al [41]

Chromo 12q24 D12S79 – D12S1718

114,444,811 – 116,237,121

LOD = 2.1

Soria et al [18]

Chromo 14 rs974673

33,550,265

3.1 × 10^-5

Yang et al [41]

Chromo 14q11 D14S72 – D14S50

20,340,828 – 21,525,933

LOD = 3.12

Soria et al [18]

Chromo 17, 96 cM

67,937,333 – 68,137,655

LOD = 1.4

Yang et al [51]

Chromo 17, 93 cM (African Americans)

66,019,673 – 66,220,040

LOD = 1.95

Ding et al [41]

Chromo 21, 13.05 cM fibrinogen and CRP (bivariate) (Non-Hispanic Whites)

20,322,875–20,523,182

LOD = 3.03

Ding et al [41]

Best et al. BMC Medical Genetics 2008 9:77   doi:10.1186/1471-2350-9-77