|
Pairwise SNP Analysis |
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| SNP |
Interaction |
Joint effect of SNP and rs2014307 |
Effect of SNP, controlling for rs2014307 |
Odds Ratio (95% C.I.) |
Effect of rs2014307, controlling for SNP |
Odds Ratio (95% C.I.) |
|
|
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| rs800292 |
0.034082688 |
1.51E-06 |
0.0005 |
0.369(0.151–0.899) |
0.0193 |
0.271(0.122–0.603) |
| rs572515 |
0.560883637 |
2.03E-10 |
0.0003 |
4.817(2.236–10.379) |
3.7602E-06 |
0.233(0.096–0.562) |
| rs7529589 |
0.454600765 |
7.27E-09 |
0.0007 |
7.861(2.283–27.066) |
0.0001 |
0.260(0.112–0.605) |
| rs1061170 |
0.597380515 |
2.22E-08 |
0.0007 |
6.831(2.113–22.079) |
0.0002 |
0.258(0.111–0.600) |
| rs12038333 |
0.393546389 |
4.22E-08 |
0.0006 |
2.884(1.512–5.503) |
0.0004 |
0.272(0.121–0.609) |
| rs203674 |
0.463309999 |
2.68E-09 |
0.0007 |
3.721(1.847–7.496) |
0.0001 |
0.256(0.109–0.603) |
| rs10801575 |
0.808299262 |
1.49E-11 |
4.0182E-05 |
0.309(0.135–0.710) |
0.0078 |
0.194(0.079–0.475) |
| rs1853883 |
0.760773267 |
9.31E-08 |
0.0004 |
2.448(1.355–4.421) |
0.0021 |
0.263(0.117–0.589) |
| rs3790414 |
0.088493626 |
2.96E-06 |
0.0001 |
0.463(0.213–1.004) |
0.0411 |
0.252(0.115–0.554) |
| rs1759016 |
0.873846771 |
9.04E-07 |
0.0001 |
0.490(0.266–0.902) |
0.0244 |
0.246(0.111–0.545) |
| rs10922152 |
0.876195836 |
1.15E-07 |
0.0002 |
0.484(0.282–0.831) |
0.0056 |
0.245(0.107–0.558) |
| rs10922153 |
0.518399094 |
2.99E-09 |
0.0006 |
0.413(0.232–0.736) |
0.0052 |
0.259(0.110–0.606) |
| rs6663083 |
0.989583181 |
6.89E-08 |
0.0001 |
0.443(0.258–0.761) |
0.0015 |
0.223(0.095–0.523) |
| rs2990510 |
0.487660055 |
4.62E-06 |
3.9350E-05 |
2.894(0.874–9.585) |
0.0684 |
0.222(0.099–0.499) |
| rs6003 |
0.454199074 |
4.15E-07 |
0.0001 |
0.151(0.035–0.649) |
0.0048 |
0.222(0.098–0.501) |
| rs1412632 |
0.396769175 |
5.61E-07 |
0.0001 |
0.164(0.038–0.697) |
0.0066 |
0.226(0.100–0.509) |
| rs1412631 |
0.64561949 |
2.26E-07 |
0.0001 |
0.113(0.021–0.592) |
0.0025 |
0.234(0.104–0.527) |
| rs12677 |
0.500827762 |
5.73E-07 |
0.0002 |
0.132(0.025–0.707) |
0.0068 |
0.239(0.108–0.528) |
| rs4915337 |
0.313727331 |
1.02E-06 |
0.0001 |
0.176(0.040–0.782) |
0.0127 |
0.239(0.108–0.528) |
| rs1888991 |
0.454199074 |
4.15E-07 |
0.0001 |
0.151(0.035–0.649) |
0.0048 |
0.222(0.098–0.501) |
| rs6677082 |
0.454199074 |
4.15E-07 |
4.8640E-05 |
0.151(0.035–0.649) |
0.0048 |
0.222(0.098–0.501) |
| rs6656448 |
0.707806912 |
1.10E-06 |
0.0001 |
0.224(0.062–0.809) |
0.0136 |
0.236(0.106–0.525) |
|
Abbreviations: SNP, Single Nucleotide Polymorphism; C.I., Confidence Interval. | ||||||
Zhang et al. BMC Medical Genetics 2008 9:51 doi:10.1186/1471-2350-9-51 |
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