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Up/down regulated genes in PBMC lacking ARHGAP4 |
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| Gene Name |
Description |
aFold change |
b q value |
cAccession |
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| Up-regulation |
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|
|
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| PLK3 |
Polo-like kinase 3 |
4.35 |
0.0402 |
NM_004073 |
| NHSL2 |
NHS-like 2 |
2.38 |
0.0453 |
NM_001013627 |
| PTAFR |
Platelet-activating factor receptor |
2.27 |
0.0288 |
NM_000952 |
| KLHL26 |
Kelch-like 26 |
1.99 |
0.0272 |
NM_018316 |
| MAPKAPK2 |
Mitogen-activated protein kinase- activated protein kinase 2 |
1.96 |
0.0442 |
NM_032960 |
| CKAP4 |
Cytoskeleton-associated protein 4 |
1.85 |
0.0272 |
NM_006825 |
| CYB5R3 |
Cytochrome b5 reductase 3 |
1.82 |
0.0328 |
NM_007326 |
| ZC3H12A |
Zinc finger CCCH-type containing |
1.81 |
0.0428 |
NM_025079 |
| FURIN |
Furin |
1.79 |
0.0448 |
NM_002569 |
| GRN |
Granulin |
1.76 |
0.0453 |
NM 002087 |
| PPOX |
Protoporphyrinogen oxidase |
1.75 |
0.0307 |
NM_000309 |
| NQO2 |
NAD(P)H dehydrogenase, quinone 2 |
1.74 |
0.0453 |
NM_000904 |
| DPH3 |
Diphthamide biosynthesis protein 3 |
1.70 |
0.0307 |
NM_206831 |
| PGD |
Phosphogluconate dehydrogenase |
1.68 |
0.00562 |
NM_002631 |
| RIPK5 |
Receptor interacting protein kinase 5 |
1.66 |
0.0386 |
NM_015375 |
| CD14 |
CD14 molecule |
1.62 |
0.0272 |
NM_000591 |
| PGD |
Phosphogluconate dehydrogenase |
1.57 |
0.0272 |
NM_002631 |
| Down-regulation |
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| TUSC4 |
Tumor suppressor candidate 4 |
0.63 |
0.0453 |
NM_006545 |
| PLEKHG4 |
Pleckstrin homology domain containing, family G (with RhoGef |
0.62 |
0.0272 |
NM_015432 |
| SFXN1 |
Sideroflexin 1 |
0.61 |
0.0272 |
NM_022754 |
| GNRH1 |
Gonadotropin-releasing hormone 1 |
0.60 |
0.0328 |
NM_000825 |
| PPP1R3E |
Protein phosphatase 1, regulatory |
0.60 |
0.0383 |
XM_940069 |
| MC1R |
Melanocortin 1 receptor |
0.56 |
0.0272 |
NM_002386 |
| LRCH4 |
Leucine-rich repeats and calponin homology (CH) domain containing 4 |
0.55 |
0.0411 |
NM_002319 |
| LOC642787 |
Hypothetical protein LOC642787 |
0.44 |
0.0288 |
XM_926202 |
| SGPP2 |
Sphingosine-1-phosphate phosphotase |
0.09 |
0.0307 |
XM_938742 |
| BNIPL |
BCL2/adenovirus E1B 19 kD |
0.06 |
0.0226 |
NM_138278 |
| ARHGAP4 |
Rho GTPase activating protein 4 |
0.00 |
0.000567 |
NM_001666 |
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aThe fold change was determined by calculating the ratio of global normalized signals from the PBMCs of NDI patients to those from the PBMCs of normal subjects. bP values corrected by the Benjamini and Hochberg false discovery rate, and expressed as q values cGenBank accession numbers | ||||
Fujimoto et al. BMC Medical Genetics 2008 9:42 doi:10.1186/1471-2350-9-42 |
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