Table 2

Immunological evaluation of NDI patients


III-3
32 yr
III-4
29 yr
IV-4
5 yr
Normal range (adult)
Normal range (children)

CD3+ [%]
74.3
68.9
85.9
55–78
55–83
CD4+/CD3+ [%]
54.9
17.7
69.6
28–57
27–53
CD8+/CD3+ [%]
34.5
61.8
14
10–39
19–34
CD4/CD8
1.6
0.3
5
1.0–3.6
0.9–2.6
CD19+ [%]
5.2
5.7
6.7
6–19
10–31

IgG (mg/dl)
810.0
741.0
754.0
870–1700
600–1450
IgA (mg/dl)
147.0
72.0
105.0
110–410
39–233
IgM (mg/dl)
59.0
127.0
72.0
33–190
69–268

TREC/μgDNA
1.9 × 102
2.8 × 102
1.6 × 103
3.4 ± 3.6 × 102
3.5 ± 2.8 × 103

The normal range of the lymphocyte subpopulation was lower and the upper confidence limit at a confidence level of 0.95. The normal range of IgG, IgA, and IgM are calculated as mean - 2SD (lower) and mean + 2SD (upper). The normal range of TREC is expressed as mean ± SD.

Fujimoto et al. BMC Medical Genetics 2008 9:42   doi:10.1186/1471-2350-9-42