Figure 3.

Schematic of FAM5C gene structure and pairwise LD between FAM5C SNPs. (A) Sixteen of forty-seven tagSNPs in FAM5C that were tested for replication and linkage are shown. SNPs with an open arrow are found outside of the gene. All sixteen SNPs represent 16 of 47 linkage disequilibrium (LD) blocks. (B) LD was estimated in one unaffected Caucasian individual from each non-redundant GENECARD ACS sibling pair. A similar pattern of LD was observed using the CATHGEN MI affected and unaffected individuals.