|
Characteristics of the 1,794 Japanese subjects used in the association tests |
||
| Stage 1 samples (discovery panel) |
Cases (n = 372) |
Controls (n = 360) |
|
|
||
| Gender (M/F) |
188/184 |
148/212 |
| Age |
64.4 ± 10.3 |
46.3 ± 19.9 |
| HbA1C (%) |
7.39 ± 1.48 |
4.79 ± 0.36 |
| BMI (kg/m2) |
23.7 ± 3.5 |
22.0 ± 2.9 |
| Age at onset < 50 (%) |
175 (47.0) |
- |
| ≥50(%) |
195 (52.5) |
- |
| unknown (%) |
2 (0.5) |
- |
| Family history (%) |
125 (33.6) |
- |
| Diabetes in both parents |
11 |
|
| Diabetes in one parent |
110 |
|
| Diabetes in son or daughter |
4 |
|
| Insulin therapy (+) (%) |
112 (30.1) |
- |
|
|
||
| Stage 2 samples (replication panel) |
Cases (n = 532) |
Controls (n = 530) |
|
|
||
| Gender (M/F) |
246/286 |
284/246 |
| Age |
62.0 ± 10.7 |
37.8 ± 11.3 |
| HbA1C (%) |
7.47 ± 1.43 |
4.88 ± 0.33 |
| BMI (kg/m2) |
23.6 ± 3.3 |
22.4 ± 3.0 |
| Age at onset < 50 (%) |
244 (45.9) |
- |
| ≥50(%) |
287 (53.9) |
- |
| unknown (%) |
1 (0.2) |
- |
| Family history (%) |
207 (38.9) |
- |
| Diabetes in both parents |
22 |
|
| Diabetes in one parent |
180 |
|
| Diabetes in son or daughter |
5 |
|
| Insulin therapy (+) (%) |
172 (32.3) |
- |
|
|
||
| Stage 1 + Stage 2 combined samples |
Cases (n = 904) |
Controls (n = 890) |
|
|
||
| Gender (M/F) |
434/470 |
432/458 |
| Age |
63.0 ± 10.6 |
41.2 ± 15.9 |
| HbA1C (%) |
7.43 ± 1.45 |
4.84 ± 0.34 |
| BMI (kg/m2) |
23.6 ± 3.4 |
22.3 ± 3.0 |
| Age at onset < 50 (%) |
419 (46.4) |
- |
| ≥50(%) |
482 (53.3) |
- |
| unknown (%) |
3 (0.3) |
- |
| Family history (%) |
332 (36.7) |
- |
| Diabetes in both parents |
33 |
|
| Diabetes in one parent |
290 |
|
| Diabetes in son or daughter |
9 |
|
| Insulin therapy (+) (%) |
284 (31.4) |
- |
Yamaguchi et al. BMC Medical Genetics 2008 9:22 doi:10.1186/1471-2350-9-22 |
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