Table 5

Sensitivity and specificity at the conventional thresholds

Model

Conventional threshold

Sensitivity at conventional threshold

Specificity at conventional threshold


All

Low risk subset

High risk subset

All

Low risk subset

High risk subset


BRCA status

BRCAPRO

10

0.75

0.63

0.82

0.62

0.70

0.58

Manchester

15

0.58

0.39

0.64

0.71

0.73

0.72

Penn II

10

0.93

0.94

0.92

0.31

0.14

0.40

Myriad II

10

0.71

0.66

0.74

0.63

0.65

0.62

FHAT

10

0.70

0.34

0.89

0.63

0.85

0.51

IBIS

10

0.20

-

-

0.74

-

-

BOADICEA

10

0.70

0.63

0.74

0.65

0.70

0.62


Panchal et al. BMC Medical Genetics 2008 9:116   doi:10.1186/1471-2350-9-116

Open Data